Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gli1  GLI-Kruppel family member GLI1   (Synonyms: Zfp5, Zfp-5)
Results	Reference
1	J:314668 Abrams SR, Reiter JF, Ciliary Hedgehog signaling regulates cell survival to build the facial midline. Elife. 2021 Oct 21;10:e68558
1	J:78687 Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN, Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development. 2002 Oct;129(19):4613-25
1	J:112463 Borello U, Berarducci B, Murphy P, Bajard L, Buffa V, Piccolo S, Buckingham M, Cossu G, The Wnt/{beta}-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis. Development. 2006 Sep;133(18):3723-32
1	J:161813 Chilov D, Sinjushina N, Saarimaki-Vire J, Taketo MM, Partanen J, beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region. PLoS One. 2010;5(6):e10881
1	J:290813 Fiore L, Takata N, Acosta S, Ma W, Pandit T, Oxendine M, Oliver G, Optic vesicle morphogenesis requires primary cilia. Dev Biol. 2020 Jun 15;462(2):119-128
1*	J:17485 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13
1	J:253972 Hwang SH, White KA, Somatilaka BN, Shelton JM, Richardson JA, Mukhopadhyay S, The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner. Development. 2018 Jan 8;145(1):dev154054
1	J:251202 Jeong MH, Leem YE, Kim HJ, Kang K, Cho H, Kang JS, A Shh coreceptor Cdo is required for efficient cardiomyogenesis of pluripotent stem cells. J Mol Cell Cardiol. 2016 Apr;93:57-66
1*	J:79831 Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT, Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development. 2002 Dec;129(24):5753-65
1*	J:119875 Lebel M, Mo R, Shimamura K, Hui CC, Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
1	J:69771 Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, St-Jacques B, McMahon AP, Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell. 2001 Jun 1;105(5):599-612
1	J:321504 Lex RK, Zhou W, Ji Z, Falkenstein KN, Schuler KE, Windsor KE, Kim JD, Ji H, Vokes SA, GLI transcriptional repression is inert prior to Hedgehog pathway activation. Nat Commun. 2022 Feb 10;13(1):808
1*	J:213418 Li D, Sakuma R, Vakili NA, Mo R, Puviindran V, Deimling S, Zhang X, Hopyan S, Hui CC, Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. Dev Cell. 2014 Apr 28;29(2):233-40
1*	J:49251 Matise MP, Epstein DJ, Park HL, Platt KA, Joyner AL, Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development. 1998 Aug;125(15):2759-70
1	J:95326 McDermott A, Gustafsson M, Elsam T, Hui CC, Emerson CP Jr, Borycki AG, Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation. Development. 2005 Jan;132(2):345-57
1*	J:39659 Platt KA, Michaud J, Joyner AL, Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice. Mech Dev. 1997 Mar;62(2):121-35
1*	J:103820 Reiter JF, Skarnes WC, Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7
1	J:118803 Ribes V, Otto DM, Dickmann L, Schmidt K, Schuhbaur B, Henderson C, Blomhoff R, Wolf CR, Tickle C, Dolle P, Rescue of cytochrome P450 oxidoreductase (Por) mouse mutants reveals functions in vasculogenesis, brain and limb patterning linked to retinoic acid homeostasis. Dev Biol. 2007 Mar 1;303(1):66-81
1	J:104523 Ribes V, Wang Z, Dolle P, Niederreither K, Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling. Development. 2006 Jan;133(2):351-61
1	J:79100 Riccomagno MM, Martinu L, Mulheisen M, Wu DK, Epstein DJ, Specification of the mammalian cochlea is dependent on Sonic hedgehog. Genes Dev. 2002 Sep 15;16(18):2365-78
1	J:123685 Saarimaki-Vire J, Peltopuro P, Lahti L, Naserke T, Blak AA, Vogt Weisenhorn DM, Yu K, Ornitz DM, Wurst W, Partanen J, Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain. J Neurosci. 2007 Aug 8;27(32):8581-92
1*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1*	J:110617 Stottmann RW, Berrong M, Matta K, Choi M, Klingensmith J, The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol. 2006 Jul 15;295(2):647-63
1	J:105832 Svard J, Henricson KH, Persson-Lek M, Rozell B, Lauth M, Bergstrom A, Ericson J, Toftgard R, Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway. Dev Cell. 2006 Feb;10(2):187-97
1	J:149516 Szabo NE, Zhao T, Cankaya M, Theil T, Zhou X, Alvarez-Bolado G, Role of neuroepithelial Sonic hedgehog in hypothalamic patterning. J Neurosci. 2009 May 27;29(21):6989-7002
1*	J:53903 Theil T, Alvarez-Bolado G, Walter A, Ruther U, Gli3 is required for Emx gene expression during dorsal telencephalon development. Development. 1999 Aug;126(16):3561-71
1	J:138862 Warr N, Powles-Glover N, Chappell A, Robson J, Norris D, Arkell RM, Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. Hum Mol Genet. 2008 Oct 1;17(19):2986-96
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1	J:321170 Zhang R, Lee C, Lawson LY, Svete LJ, McIntyre LM, Harfe BD, SHH Protein Variance in the Limb Bud Is Constrained by Feedback Regulation and Correlates with Altered Digit Patterning. G3 (Bethesda). 2017 Mar 10;7(3):851-858
1	J:108746 Zhang W, Kang JS, Cole F, Yi MJ, Krauss RS, Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly. Dev Cell. 2006 May;10(5):657-65
1	J:177881 Zhang Z, Wlodarczyk BJ, Niederreither K, Venugopalan S, Florez S, Finnell RH, Amendt BA, Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One. 2011;6(9):e24608
1	J:219584 Zhulyn O, Hui CC, Sufu and Kif7 in limb patterning and development. Dev Dyn. 2015 Mar;244(3):468-78
1	J:213417 Zhulyn O, Li D, Deimling S, Vakili NA, Mo R, Puviindran V, Chen MH, Chuang PT, Hopyan S, Hui CC, A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers. Dev Cell. 2014 Apr 28;29(2):241-9
1	J:87046 Zoltewicz JS, Stewart NJ, Leung R, Peterson AS, Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development. 2004 Jan;131(1):3-14